Organic, non-GMO, full-spectrum CBD HOW DOES CBD OIL WORK? Your body has something called an Endocannabinoid System (ES). This is one of the most important systems in the body when it comes to building and maintaining health. Its role is to balance everything. There are two types of cannabinoid receptors in your body: CB1 receptors, found mostly in the brain and central nervous system (CNS), and CB2 receptors, found throughout the rest of the body (the organs, the glands, and probably most important, the immune system). Your body produces endocannabinoids and these interact with the cannabinoid receptors throughout your body. You can increase the cannabinoids in your body with CBD oil.